(1R,3R)-Methyl 1-(Benzo[D][1,3]Dioxol-5-Yl)-2-(2-Chloroacetyl)-2,3,4,9-Tetrahydro-1H-Pyrido[3,4-B]Indole-3-Carboxylate

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Home > API & Intermediate > Pharmaceutical Intermediates > (1R,3R)-Methyl 1-(Benzo[D][1,3]Dioxol-5-Yl)-2-(2-Chloroacetyl)-2,3,4,9-Tetrahydro-1H-Pyrido[3,4-B]Indole-3-Carboxylate Manufacturers > (1R,3R)-Methyl 1-(Benzo[D][1,3]Dioxol-5-Yl)-2-(2-Chloroacetyl)-2,3,4,9-Tetrahydro-1H-Pyrido[3,4-B]Indole-3-Carboxylate

(1R,3R)-Methyl 1-(Benzo[D][1,3]Dioxol-5-Yl)-2-(2-Chloroacetyl)-2,3,4,9-Tetrahydro-1H-Pyrido[3,4-B]Indole-3-Carboxylate

CAS NO.： 171489-59-1

FOB Price： NEGOTIABLE Get Latest Price

Specification： 98%

Documentation： Get COA after inquiry

Lead Time： 30-60 days

Max Capacity： -

Packing： 25KG/Fibre Drum; Customed Package

Product Detail

Properties

(1R,3R)-Methyl 1-(Benzo[D][1,3]Dioxol-5-Yl)-2-(2-Chloroacetyl)-2,3,4,9-Tetrahydro-1H-Pyrido[3,4-B]Indole-3-Carboxylate

English Name: (1R,3R)-Methyl 1-(Benzo[D][1,3]Dioxol-5-Yl)-2-(2-Chloroacetyl)-2,3,4,9-Tetrahydro-1H-Pyrido[3,4-B]Indole-3-Carboxylate

CAS No.: 171489-59-1

Molecular formula: C22H19ClN2O5

Molecular weight: 426.85

Melting point: 230-232 ℃

Boiling point: 627.5 ± 55.0 ° C (predicted)

Density: 1.445g/cm3

Application: tadalafil intermediate can be used as organic synthesis intermediate and pharmaceutical intermediate, and can be used in laboratory R & D process and chemical pharmaceutical synthesis process.

Properties

This product is an intermediate of tadalafil, which can be used in laboratory research and development process and chemical medicine synthesis process. Tadalafil is a selective reversible inhibitor of cyclic guanosine monophosphate (CGMP) - specific phosphodiesterase 5 (PDE5). When sexual stimulation results in the local release of nitric oxide, PDE5 is inhibited by tadalafil, which increases the cGMP level in the penile cavernous body, resulting in relaxation of smooth muscle, blood flow into the penile tissue, and erection, such as asexual stimulation.

CAS No.

171489-59-1

Formula

C22H19N2O5Cl

Molecular Mass

426.84966

Exact Mass

426.09800

PSA

80.86000

Logp

3.08900

IUPAC

methyl (1R,3R)-1-(1,3-benzodioxol-5-yl)-2-(2-chloroacetyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-3-carboxylate

Matter Classification

organic

Category

Melting Point

230-232℃

Density

1.445 g/cm3

Boiling Point

627.5 °C

Appearance

white solid

Acidity and Basicity

alkalinity, acidness

HS Code

29339900

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